Science & Active Ingredients

RE SKIN develops skincare based on skin biology – not on trends. This page provides an overview of the active ingredients and principles that define our formulations, as well as the scientific foundations upon which we build them.

Our Approach

We believe in skincare that works with the skin – not against it. Therefore, we rely on well-researched active ingredients, skin-mimicking formulations, and a minimalist, well-considered combination of individual components. The goal is to support the skin in rebalancing its natural functions.

Matrixyl® Peptides

Peptides such as Palmitoyl Pentapeptide‑4 (Matrixyl®) act as signaling molecules in the skin. Studies show that certain peptides can support collagen synthesis and thus contribute to improved skin structure. In cosmetic formulations, they are used to assist the skin in its regenerative processes – without irritating or overwhelming the skin.

Oligomeric & Modified Hyaluronic Acids

Hyaluronic acid is a natural component of the skin and plays a central role in moisture, elasticity, and cell communication. Different molecular sizes fulfill different functions. Low-molecular-weight and modified forms can intensely hydrate the skin's surface and support the absorption of other active ingredients.

Skin-Identical DMS Lipids Systems

DMS (Derma Membrane Structures) systems mimic the natural structure of the skin barrier. They consist of skin-related lipids and are free of traditional emulsifiers. As a result, they are particularly well recognized and integrated by the skin – an approach especially valued for sensitive or imbalanced skin.

Stable Vitamin C Derivatives

Vitamin C is a key active ingredient in dermatological research. Stable derivatives ensure good tolerability and protect the skin from oxidative stress. Studies show that Vitamin C can support skin structure and be involved in collagen formation, without unnecessarily irritating the skin.

Our Understanding of Efficacy

For us, efficacy does not mean immediate effects, but rather understandable, biologically meaningful processes. Every active ingredient at RE SKIN is used in a way that supports the skin – not dominates it.

Scientific Foundations (Selection)

The active ingredients and principles described here are based, among other things, on published dermatological and biochemical studies on peptides (Matrixyl®), hyaluronic acid, vitamin C, and skin-identical lipid systems.

Studies & Sources (Selection)

Peptides (Matrixyl® / Palmitoyl Pentapeptide‑4)
– National Library of Medicine (PMC): Mechanism of action and influence on collagen synthesis
https://pmc.ncbi.nlm.nih.gov/articles/PMC11762834/

– British Journal of Dermatology: Clinical evaluation of cosmetic peptides
https://academic.oup.com/bjd/article/189/Supplement_1/i17/7333865

Hyaluronic Acid (incl. modified / low molecular weight forms)
– MDPI Biomolecules: Biological functions of hyaluronic acid in the skin
https://www.mdpi.com/2218-273X/15/12/1656

– PubMed: Modified hyaluronic acid and skin penetration
https://pubmed.ncbi.nlm.nih.gov/40715158/

Vitamin C (topical, stabilized forms)
– National Library of Medicine (PMC): Vitamin C in dermatology
https://pmc.ncbi.nlm.nih.gov/articles/PMC5605218/

– Journal of Clinical and Aesthetic Dermatology: Mechanisms of action and clinical application of Vitamin C
https://jcadonline.com/topical-vitamin-c-and-the-skin-mechanisms-of-action-and-clinical-applications/

Skin-identical Lipid Systems / Barrier Structures
– MDPI: Skin Barrier Lipids and Barrier Function
https://www.mdpi.com/1422-0067/19/1/70